the effect of naf mouthrinse, gc tooth mousse and gc mi paste plus on white spot inhibition: an invitro study

introduction: to compare the effects of 0.05% sodium fluoride (naf) mouthrinse, gc tooth mousse and gc mi paste plus on white spot formation inhibition. materials and methods: thirty pairs of extracted human premolars were cut in half mesio-distally with a disc. the teeth were coated with nail varnish, except a part of the buccal and/or lingual enamel, which was used as the test area, and then divided into 4 groups randomly: a) control, b) 0.05% nafmouthrinse, c) tooth mousse, d) mi paste plus. therapeutic agents were applied once daily following the manufacturer’s directions in a ph-cycling model over 35 days. at the end of the experiment, all the specimens were examined in order to detect white spot formation before and after drying (scoring 0-2). mann whitney test was used for statistical analysis. results: the mean of the white spot scores in groups b (0.16), c (1.4) and d (1.2) were significantly lower than group a (2). significantly lower mean of white spot scores was found in nafmouthrinse group compared with two other products. no significant difference was observed between tooth mousse and mi paste plus. conclusion: although 0.05% naf mouthrinse, gc tooth mousse and gc mi paste plus are effective preparations to inhibit white spot formation, nafmouthrinse has better efficacy than cpp-acp (casein phosphopeptide-amorphous calcium phosphate) products.